#TOLL2024

Luke O’Neill

Lecture Title: A break in mitochondrial endosymbiosis as a basis for inflammatory diseases

Luke O’Neill is Professor of Biochemistry in the School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute at Trinity College Dublin, Ireland. He is a world expert on innate immunity and inflammation. His main research interests include Toll-like receptors, Inflammasomes and Immunometabolism. He is listed by Thompson Reuters/ Clarivates in the top 1% of immunologists in the world, based on citations per paper. Professor O’Neill is co-founder of Sitryx, which aims to develop new medicines for inflammatory diseases. Another company he co-founded, Inflazome, which developed NLRP3 inhibitors, was acquired by Roche which are currently in clincal trials for inflammatory indications.