Lecture Title: IRG1-itaconate Axis in Lipid Homeostasis and Atherosclerosis
Dr. Kathryn Moore is the Jean and David Blechman Professor of Cardiology, and Director of the Cardiovascular Research Center at New York University’s Grossman School of Medicine. She is internationally recognized for her research on the molecular pathogenesis of cardiometabolic diseases, particularly the roles that non-coding RNAs and dysregulated immune responses play in those disorders. By forging new links between lipids, metabolism and innate immunity, her discoveries have revealed fundamental insights into pathways that regulate cholesterol homeostasis and vascular inflammation.
Dr. Moore received her B.Sc. and Ph.D. from McGill University in Canada. Although her early research focused on the immune response to pathogens, she became fascinated with the mechanisms of chronic inflammation, and pursued postdoctoral training at Harvard Medical School in the areas of autoimmune and atherosclerotic cardiovascular disease. She served on the faculty of Harvard Medical School and Massachusetts General Hospital (Dept of Medicine) until 2009, before moving to New York University School of Medicine, where she is a tenured professor in the departments of Medicine and Cell Biology.
Dr. Moore’s contributions to the fields of innate immunity and vascular biology have been recognized by numerous awards and honors, including the NIH’s Outstanding Investigator Award, Clarion’s List of Most Highly Cited Researchers (top 1%, 2018-21), the ATVB Mentor of Women Award, the American Heart Association’s Distinguished Scientist Award, and election to the National Academy of Sciences USA, among others.
